Isonimesulide and Its Carborane Analogues as Isoform‐Selective COX Inhibitors and Antitumor Agents (Adv. Therap. 8/2023)
نویسندگان
چکیده
Nimesulide is a nonsteroidal anti-inflammatory drug (NSAID) with potent properties, including potential in cancer treatment. Bioisosteric replacement of phenyl ring isonimesulide, novel isomer nimesulide, by carboranes yielded compounds COX-independent but more antitumor than nimesulide and isonimesulide. This reported Evamarie Hey-Hawkins co-workers article number 2300117. Artwork Dr. Christoph Selg.
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ژورنال
عنوان ژورنال: Advanced therapeutics
سال: 2023
ISSN: ['2366-3987']
DOI: https://doi.org/10.1002/adtp.202370022